These Coenzyme Q10 Skincare Products Energize & Protect Your Skin

Best Coenzyme Q10 Skincare Products

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As with any other good thing in our skin, coenzyme Q10, apparently, decreases with age too. There may be, however, a chance to hold on to your coenzyme Q10 a little while longer. And that’s with topical skincare. Coenzyme Q10 skincare products can help you replenish this ever-declining antioxidant. And I call that a win if ever I’ve seen one! Keep reading to learn more about the skincare benefits of coenzyme Q10 and the best skincare products to try.

What Is Coenzyme Q10?

Coenzyme Q10 (CoQ10), also known as ubiquinone, is a natural antioxidant. It’s found in the skin surface oils, which are components of what makes your protective skin barrier 1.

Because it’s an effective antioxidant and has skin-protecting abilities, coenzyme Q10 is commonly formulated into skincare products like serums and moisturizers.

Benefits of Coenzyme Q10 for Skin

1. Increases Cellular Energy

One of the most important functions of CoQ10 is providing cellular energy 2. It means that CoQ10 improves the overall workings of the skin, keeping it healthy and resilient.

2. Protects Skin

Coenzyme Q10 is an antioxidant that protects the skin from free radicals. As free radicals are responsible for causing premature wrinkles and lines, CoQ10 helps keep your skin youthful by preventing free radicals from damaging your skin’s healthy collagen and elastin.

3. Reduces Hyperpigmentation

Though coenzyme Q10 is widely praised for its antioxidant benefits, it may help with hyperpigmentation by inhibiting melanin production 3. As a result, it can help you achieve an even skin tone with less visible dark spots.

4. Works Gently on the Skin

Though CoQ10 is not as popular as other antioxidants like vitamin C, it is much gentler. This allows people with sensitive skin to utilize this ingredient in their anti-aging skincare routine. It offers a way to combat wrinkles and lines without resorting to potentially irritating ingredients that people with sensitive, reactive skin can’t tolerate.

Best Coenzyme Q10 Skincare Products

From serums to creams, find below the best coenzyme Q10 skincare products.

1. Indie Lee CoQ10 Toner

Indie Lee CoQ10 Toner - Best Coenzyme Q10 Skincare Products

This is an alcohol-free face toner you can use to balance your complexion after cleansing. It’s made with CoQ10 and also packs a bunch of skin soothers. Aloe, cucumber, and chamomile calm the skin while hyaluronic acid hydrates for softer and plumper skin. And with CoQ10, you collect the energizing and antioxidant benefits. This is a practical way to replenish diminished levels of CoQ10 in the skin.

Key Ingredients: CoQ10, hyaluronic acid, aloe, cucumber
Size: 4.2 oz/125 ml
Good To Know: Cruelty-free, vegan, alcohol-free

2. The Inkey List Q10 Antioxidant Serum

The Inkey List Q10 Antioxidant Serum - Best Coenzyme Q10 Skincare Products

This is the most budget-friendly Coenzyme Q10 skincare product out there. It’s an anti-aging serum that lightly hydrates while promoting stronger, healthier skin. It boosts hydration with squalane, glycerin, and hyaluronic acid. And to amplify the antioxidant effects of CoQ10, the serum contains vitamin E as well as signal peptides. This one can be an overall great anti-aging serum no matter your skin type. You can use it for maintaining healthy skin and also preventing premature aging.

Key Ingredients: CoQ10, peptides, squalane
Size: 1 oz/30 ml
Good To Know: Vegan, cruelty-free, fragrance-free

3. DHC Coenzyme Q10 Quick Gel Brightening Moisture

DHC Coenzyme Q10 Quick Gel Brightening Moisture

If you’re dealing with sun-damaged skin and dark spots, you can better utilize CoQ10 with this brightening moisturizer. Because it’s paired with one of the most effective antioxidants: vitamin C. The two antioxidants stave off free radicals, boost collagen production, and reduce the look of dark spots. And all that good stuff is formulated into a very moisturizing base so you get immediate skin-softening benefits too.

Key Ingredients: CoQ10, vitamin C, vitamin E
Size: 3.5 oz/100 ml
Good To Know: Fragrance-free

4. Juice Beauty Green Apple Age Defy Moisturizer

Juice Beauty Green Apple Age Defy Moisturizer - Best Natural Coenzyme Q10 Skincare Products

This is like an organic vitamin juice for the skin. And it’s all thanks to its rich formula infused with skincare superfoods. Grape juice, green tea, borage oil, and allantoin infuse the skin with natural antioxidants. On top of CoQ10, the moisturizer also contains signal peptides, vitamin C, vitamin E, and alpha-lipoic acid to boost collagen production, brighten the skin, reverse sun damage, and improve skin texture. The light cream also plumps up the skin with vitamin B5, hyaluronic acid, and squalane.

Key Ingredients: CoQ10, green tea, vitamin C
Size: 2 oz/60 ml
Good To Know: Vegan, cruelty-free

5. Sunday Riley A+ High Dose Retinol Serum

Sunday Riley A+ High Dose Retinol Serum - Best Coenzyme Q10 Skincare Products

Retinol can be really irritating to the skin. But there’s always a workaround to make it more tolerable and skin-friendly. So if you’re ready to commit, you can start with this retinol serum powered with a variety of antioxidants including CoQ10. It’s made with encapsulated retinol to avoid irritation. And it has Granactive Retinoid, a new, gentler alternative to retinoids. You get all the anti-aging and wrinkle-reducing benefits but you don’t deal with irritation.

Key Ingredients: CoQ10, retinol, Granactive Retinoid
Size: 1 oz/30 ml
Good To Know: Cruelty-free

6. Eucerin Q10 Anti-Wrinkle Face Cream

Eucerin Q10 Anti-Wrinkle Face Creme - Best Drugstore Coenzyme Q10 Skincare Products

On the flip side, if your skin doesn’t seem to tolerate anything and you really want to do something about lines and wrinkles, you can try this affordable, super gentle, fragrance-free moisturizer. That way, you don’t need to deal with the irritation that comes with mainstream anti-agers. This one is formulated with vitamin E and beta carotene to maximize the anti-wrinkle benefits. It’s non-comedogenic so it’s suitable for acne-prone skin too.

Key Ingredients: CoQ10, vitamin E
Size: 1.7 oz/48 gr
Good To Know: Alcohol-free, non-comedogenic

So these are some of the best skincare products made with coenzyme Q10. When antioxidants are concerned, the more the merrier. So look for additional antioxidants in your CoQ10 products for amplified anti-aging benefits.


Read Next: Best Antioxidant Moisturizers


  1. Knott, A., Achterberg, V., Smuda, C., Mielke, H., Sperling, G., Dunckelmann, K., Vogelsang, A., Krüger, A., Schwengler, H., Behtash, M., Kristof, S., Diekmann, H., Eisenberg, T., Berroth, A., Hildebrand, J., Siegner, R., Winnefeld, M., Teuber, F., Fey, S., Möbius, J., … Blatt, T. (2015). Topical treatment with coenzyme Q10-containing formulas improves skin’s Q10 level and provides antioxidative effects. BioFactors (Oxford, England)41(6), 383–390. ↩︎
  2. Farage, M. A., Miller, K. W., & Maibach, H. I. (2009). Energetic effects of coenzyme Q10 [E-book]. In Textbook of Aging Skin (pp. 306–309). Springer Publishing. ↩︎
  3. Hseu, Y. C., Ho, Y. G., Mathew, D. C., Yen, H. R., Chen, X. Z., & Yang, H. L. (2019). The in vitro and in vivo depigmenting activity of Coenzyme Q10 through the down-regulation of α-MSH signaling pathways and induction of Nrf2/ARE-mediated antioxidant genes in UVA-irradiated skin keratinocytes. Biochemical pharmacology164, 299–310. ↩︎
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